Drew Thieme, PhD

Dr. Thieme is a cheminformatician with deep expertise in the areas of data science, biochemical and subjective experiential data curation, computational chemistry, medicinal chemistry, psychopharmacology, pathophysiology, and drug discovery and development. He employs machine learning techniques, quantitiative structure-activity relationship modeling, molecular modeling, and biomedical knowledge graph analysis to develop virtual screening platforms oriented toward the identification of novel candidate molecules for targeted applications.

Dr. Thieme's dissertation focused on harmonizing raw subjective scent data via natural language processing, predicting subjective scent perception profiles from chemical structure of odorants, and leveraging biomedical knowledge graphs to draw connections between perceptual processes and various disease states. Additionally, Dr. Thieme has worked to formally define the concept of Clinical Outcomes Pathways, a new paradigm for the classification, characterization, and comparision of drug action. Now, at Mindstate Design Labs, Dr. Thieme is adapting these methods to the domain of subjective psychedelic experience to drive discovery of novel psychedelic drugs and precision design of modified conscious states.

Dr. Thieme holds a PhD in Pharmaceutical Sciences from the University of North Carolina at Chapel Hill and a Bachelor's Degree in Pharmaceutical Sciences from Purdue University.